Monday, March 7, 2016

Inducible vs Repressible

Compare and contrast an inducible operon and a repressible operon. Include an example of each.
Inducible: The lac operon is an example of an inducible operon. It is usually off, but can be induced to turn on when needed. In these operons, there is an active operon always attached to the operator of the operon, until an inducer attaches to it and causes it to change shape and detach. This allows for RNA polymerase to go through reading the operon, to create the protein it codes for. The lac operon codes for enzymes that are used to hydrolyze and metabolize lactose. So, this operon will only be active when there is lactose present. When lactose is present, allolactose is the inducer which will inactivate the repressor attached to the operator.  
http://biology-forums.com/index.php?action=gallery;sa=view;id=11503

Repressible: The trp operon is an example of a repressible operon. It is usually turned off, but can be repressed when it is not needed. These operons are turned off by the binding of a repressor protein, that may need a corepressor in order to be activated, to the operator of the operon. In the trp operon, tryptophan is coded for. When there is tryptophan present in the cell and does not need to be synthesized, this acts as a corepressor and causes the operon to be blocked and turned off.
http://www.slideshare.net/kindarspirit/18-regulation-of-gene-expression

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