Explain how eukaryotic cells modify RNA after transcription and why it is necessary.
Both ends of the transcript are altered to include a 5’ cap on the 5” end, and a poly-A tail on the 3’. These modifications facilitate the export of mRNA from out of the nucleus into the cytoplasm, protect mRNA from hydrolytic enzymes, and help ribosomes attach to the 5’ end of the strand. Enzymes that modify the original RNA transcript into mRNA within the nucleus also cut out interior sections of the molecule before allowing it to exit the nucleus.
Both ends of the transcript are altered to include a 5’ cap on the 5” end, and a poly-A tail on the 3’. These modifications facilitate the export of mRNA from out of the nucleus into the cytoplasm, protect mRNA from hydrolytic enzymes, and help ribosomes attach to the 5’ end of the strand. Enzymes that modify the original RNA transcript into mRNA within the nucleus also cut out interior sections of the molecule before allowing it to exit the nucleus.
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