Monday, December 21, 2015

Stages of Meiosis

Explain the events of all stages of meiosis
  • Meiosis I
    • Prophase I
      • Centrosome movement, spindle formation, nuclear envelope breaks down, chromosomes condense
      • Chromosomes align with their homolog pair, and crossing over occurs [this is the exchange of DNA between two non-sister chromatids]
      • The chiasmata is visible in this stage, this is the location where crossing over occurs
      • Microtubules from the centrosomes will begin to attach to the kinetochores of the homologous chromosome pairs
    • Metaphase I
      • Pairs of homologous chromosomes are arranged at the metaphase plate
      • Both chromatids of one homolog pair are attached to a spindle fiber on either polar side of the cell
    • Anaphase I
      • Homologs separate as proteins responsible for sister chromatid cohesion along the chromatid arms break down
      • Homologs move towards opposite poles of the cell
      • Sister chromatid stay connected to each other as they separate and move
    • Telophase I and Cytokinesis
      • Each half of cell now has a complete haploid set of duplicated chromosomes
      • Cytokinesis divides cytoplasm and splits cell in half
  • Meiosis II - NO CHROMOSOME DUPLICATION
    • Prophase I
      • Spindle apparatus forms
      • Chromosomes begin to line up along the metaphase plate
    • Metaphase I
      • Microtubules attach to kinetochores and pull apart sister chromatids
    • Anaphase I
      • Chromosomes move up the microtubules towards opposite ends of the cell
    • Telophase I and Cytokinesis
      • Nuclei form, chromosomes begin to condense
      • Cell divides

NOW, at the end of meiosis in an animal cell, the end result is four daughter cells [when starting with one cell]

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